New Born Screening

NEW BORN SCREENING PANEL – 50 METABOLIC DISORDERS BY MASS SPECTOMETRY

Royal English Laboratory provides the best possible newborn screening test in Kuwait. Newborn screening test is a practice of testing every newborn for certain harmful or potentially fatal disorders that aren’t otherwise apparent at birth.

Why newborn screening lab test?

  • Affected babies are identified quickly before symptoms appear
  • Cases of disease are not missed
  • The number of false-positive results is minimized
  • Early treatment can begin, that prevents the negative and irreversible health outcomes for affected newborns
  • Most treatments are inexpensive and may involve the addition of a vitamin to the diet, hormone supplementation, avoidance of certain foods and chemicals or dietary changes

Why early detection?

It could lead to lifelong complications, such as:

  • Mental Retardation
  • Motor Impairment
  • Physical Disability

Who to screen NBS?

  • Every Newborn (routine screening)
  • High Risk
  • Unexplained deaths of siblings
  • Miscarriages and aborted fetuses
  • Exhibit symptoms of IEMs
  • Babies conceived by IVF
  • Babies in NICU
  • Sick Children

WHAT TO SCREEN (United Laboratories)

Acylcarnitine Profile (Tandem Mass Spectrometry)

  • Fatty Acid Oxidation Disorders
  • Organic Acid Disorders

Amino Acid Profile (Tandem Mass Spectrometry)

  • Amino Acid Disorders
  • Urea Cycle Disorders

Biochemical screening (enzyme assay/enz. Immunoassay):

  • Galactosemia
  • Congenital Hypothyroidism
  • Congenital Adrenal Hyperplasia
  • G6PD Deficiency
  • Cystic Fibrosis
  • Biotinidase Deficiency

Blood Sample Collection

Sample: Blood spot is collected on filter paper

Condition:

  • Baby needs to be fed at least 2-3 times before the specimen is taken.
  • After 24 hours of birth.

TAT: 7 days

Top